Prevention and treatment of acute lung injury with time-controlled adaptive ventilation: physiologically informed modification of airway pressure release ventilation
نویسندگان
چکیده
منابع مشابه
Other approaches to open-lung ventilation: airway pressure release ventilation.
OBJECTIVE To review the use of airway pressure release ventilation (APRV) in the treatment of acute lung injury/acute respiratory distress syndrome. DATA SOURCE Published animal studies, human studies, and review articles of APRV. DATA SUMMARY APRV has been successfully used in neonatal, pediatric, and adult forms of respiratory failure. Experimental and clinical use of APRV has been shown ...
متن کاملPressure Controlled Ventilation to Induce Acute Lung Injury in Mice
Murine models are extensively used to investigate acute injuries of different organs systems. Acute lung injury (ALI), which occurs with prolonged mechanical ventilation, contributes to morbidity and mortality of critical illness, and studies on novel genetic or pharmacological targets are areas of intense investigation. ALI is defined by the acute onset of the disease, which leads to non-cardi...
متن کاملP32: Effect of Airway Pressure Release Ventilation Mode on Intracranial Pressure and Oxygenation in Patients with Traumatic Brain Injuries
This study aimed at compare influences of airway pressure release ventilation (APRV) and Synchronized Intermittent Mechanical Ventilation (SIMV) on intracranial pressure and oxygenation status in patients with traumatic brain injuries. A clinical trial was carried out in 40 patients with traumatic brain injuries in the intensive care unit in Kamyab neurosurgery Hospital, Mashhad, Iran. The pati...
متن کاملAirway pressure release ventilation and successful lung donation.
HYPOTHESIS Donor management with airway pressure release ventilation (APRV) improves oxygenation and increases lung donation while maintaining equivalent graft survival. DESIGN Retrospective case series. SETTING Private, tertiary care, level I trauma center. PATIENTS Forty-five consecutive organ donors. INTERVENTIONS Management with assist/control ventilation (ACV) or APRV. MAIN OUTCO...
متن کاملEffects of short-term pressure-controlled ventilation on gas exchange, airway pressures, and gas distribution in patients with acute lung injury/ARDS: comparison with volume-controlled ventilation.
STUDY OBJECTIVES The potential clinical benefits of pressure-controlled ventilation (PCV) over volume-controlled ventilation (VCV) in patients with acute lung injury (ALI) or ARDS still remain debated. We compared PCV with VCV in patients with ALI/ARDS with respect to the following physiologic end points: (1) gas exchange and airway pressures, and (2) CT scan intrapulmonary gas distribution at ...
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ژورنال
عنوان ژورنال: Annals of Intensive Care
سال: 2020
ISSN: 2110-5820
DOI: 10.1186/s13613-019-0619-3